CETIM COBRA by CETIM. Versions: 6.1, 5.5 and 5.2. File name: Cobra.exe. Cetim Cobra Software. CAO- formation, le portail des formations continues en CAO, FAO, IAO, PDM,. Manage your page to keep your users updated View some of our. Packages • The COnstraint-Based Reconstruction and Analysis (COBRA) Toolbox written in MATLAB. • • COBRApy is a package for constraint-based modeling of biological networks written in Python. • • High-level, high-performance, constraint-based reconstruction and analysis in Julia. • • Linux, Windows and Mac binaries maintained by the constraint-based reconstruction and analysis (COBRA) community. • • The Mass-Action Stoichiometric Simulation (MASS) toolbox enables the construction and analysis of kinetic and constraint-based models. • • Make a contribution to any git repository from MATLAB. The devTools are cross-platform, for novice and advanced users. Contribute the smart way! What is COBRA? The COnstraints Based Reconstruction and Analysis ( COBRA) approach to systems biology accepts the fact that we do not possess sufficiently detailed parameter data to precisely model, in the biophysical sense, an organism at genome-scale. Increasingly, omics data has been used to define the set of feasible states for a biological network in a given condition based on current knowledge. These constraints include compartmentalization, mass conservation, molecular crowding, and thermodynamic directionality. More recently, transcriptome data have been used to reduce the size of the set of computed feasible states. Although COBRA methods may not provide a unique solution, they provide a reduced set of solutions that may be used to guide biological hypothesis development.
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